Both teams go into the clash out of form results wise, sharing a ten game winless run between them.
The Millers will be looking to draw on their two wins over City last season for inspiration as both teams won promotion from League Two.
The gaffer told BBC Radio Sheffield: "It's a great occasion in a great stadium and I'm looking forward to it.
"It's the tie of the round and why the television cameras aren't here is a mystery. It's a Yorkshire derby with both clubs doing well in League One, with two special sets of supporters and decent squads. I think both clubs would grace the Championship but you have to earn the right to be there.
"I think the game will have a physical element but there will also be a footballing element as both teams have got outstanding footballers and players who are winners.
"The midfield will be a key area on Saturday. It's got all the ingredients of being a great cup tie and I want to remember it on Saturday night for all the right reasons."